Asthenospermia
Conditions
Interventions
1:administration Sheng Jing San
2:administration Levocarnitine
3:administration placebo
Sponsors
Neuroscience Research Instituteand Department of Neurobiology, Peking University, Beijing China
Eligibility
Sex/Gender
Male
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Conforming to the diagnosis of traditional Chinese Medicine of male sterility and diagnosis standard of western medicine of weak sperm; 2. Age from 20 to 40; 3. Whose main reason of male sterility is weak sperm; 4. Medical history over one year; 5. Those who are informed.
Exclusion criteria
Exclusion criteria: 1. Clearly primary weak sperm, or secondary organic weak sperm (shaft, chromosomal abnormalities); 2. The patient can not be safely continued treated; 3. The patient has a medical history of some other serious familial hereditary disease in the recent six months, such as leukemia, hemophilia and so on; 4. Combined with serious diseases of other systems, such as decompensated heart failure, severe liver function damage (serum transaminase >=2*medical reference value upper limit, creatinine clearance rate<=40 ml/min or nephropathy in active stage); 5. Allergic constitution, surely or possibly allergy to chinese herbal medicine (including previous chinese herbal decoction or those makes people become palpitations, facial flushing,headache, hypotension, edema of lower extremity and other adverse reactions); 6. Already having bleeding tendency or bleeding disease, or coagulation disorders out of control, or active bleeding in two weeks and treatment of invasive operation, or severe trauma or operation history in twelve weeks; 7. Seriously primary diseases and mental disease influential to life, or those who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sperm concentration;Sperm motility;Sperm morphology;Seminal plasma biochemistry;The expression of the CatSper channel protein; | — |
Countries
China
Contacts
Public ContactXING Guo-gang
Outcome results
None listed