Osteoarthritis
Conditions
Interventions
Sponsors
Agricultural Research Development Agency
Eligibility
Sex/Gender
Male
Age
25 Years to No maximum
Inclusion criteria
Inclusion criteria: Out-patients of either sex, age over 25, suffer ing from OA of knee (unilateral or bilateral) according to the criteria of the American College of Rheumatoloy as: knee pain and radiographic osteophytes and at least 1 of the following 3 items: age over 50 years, morning stiffness not more than 30 min in duration, or crepitus on motion. The symptoms must be present for more than 3 months. After stop using usual medications for 7 days, VAS of total pain must be > or = 200 and < or = 350. Participants must be capable of walking. All patients have to sign the written consent form to participate in the study.
Exclusion criteria
Exclusion criteria: Patients must not have the following diseases or conditions: an underlying inflammatory arthropathy, acute or chronic gouty arthritis, hyperuricemia > 9 mg/dl with or without history of gouty attack, expectation of surgery in the near future, recent injury in the area affected by OA of knee, active inflammation of OA of knee, significant knee joint effusion, intra-articular corticosteroid injections within the last 3 months, continuous use of the symptomatic slow-acting drugs for osteoarthritis (SYSDOA) [e.g., glucosamine sulphate, chondroitin sulphate, diacerein, and hyaluronic acid] less than 4 months or stop using these drugs less than 6 months, hypersensitivity to NSAIDs, concomitant skin disease at the application site, pregnancy and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of Responsder; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS of pain;VAS of stiffness;Lequense's functional index; | — |
Countries
Thailand
Contacts
Public ContactAssoc. Prof. Dr. Supanimit Teekachunhatean
Outcome results
None listed