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The Efficacy of ?-3 Fatty Acid-Based Parenteral Nutrition for Liver Cancer after Hepatectomy

The Efficacy of ?-3 Fatty Acid-Based Parenteral Nutrition for Liver Cancer after Hepatectomy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-11001715
Enrollment
Unknown
Registered
2011-11-14
Start date
2010-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver cancer

Interventions

Group 1:20% Structolipid only
Group 2:20% Structolipid and 10% Omegaven

Sponsors

Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 74 Years

Inclusion criteria

Inclusion criteria: Patients performed hepatectomy as a result of liver cancer were enrolled who had malnourished preoperatively according to Subjective Global Assessment(SGA). They were considered malnourished if they met either or both of two criteria: (1) a score of 100 or less on the Nutrition Risk Index(NRI), calculated according to the following formula: 1.519*the serum albumin level(g/L)+0.417*(current weight/usual weight)*100 or (2) any two of the following: a current weight that was 95 percent of the ideal weight or less; a serum albumin level of 35.0g per liter or less; or a serum prealbumin level of 200mg per liter or less.

Exclusion criteria

Exclusion criteria: Exclusion criteria were upper gastrointestinal hemorrhage, severe hemorrhagic disorders, explicit acute infectious lesion, overt ascites, Child-Pugh Score C, indocyanine green retention rate at 15min(ICGR15)>30%, serum HBV-DNA>1000K copies/ml and serum alanine aminotransferase>2*ULN, serum triglycerides>2.0mmol/L, circulatory shock, stroke, acute myocardial infarction, renal failure,coma of unknown cause, pregnancy, age of75 yrs, and allergic reactions against fish or egg proteins.

Design outcomes

Primary

MeasureTime frame
liver function;endoscope;blood routine;coagulation routine;urine output;biochemistry variable;intraoperative characteristics;type of hepatectomy;postoperative profiles;postoperative complication;

Countries

China

Contacts

Public ContactGang Wei
weigang2004@medmail.com.cn+86 13797021206

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026