primary liver cancer
Conditions
Interventions
A:preoperative conformal radiotherapy combined with precision centripetalism resection
B:precision centripetalism resection
Sponsors
Eastern Hepatobiliary Surgical Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. 20 to 70 years old male or non-pregnant female hepatocellular carcinoma patient; 2. Portal vein tumor thrombus, I, II, III-type (Cheng SQ, et al. Hepato-Gastroenterology 2007; 54: 499-502); 3. Pathologically proved HCC, single tumor <10cm in diameter, without extrahepatic metastasis or adjacent organ involvement before surgery; 4. BCLC stage is either A or B, liver function is Child-Pugh A or B; 5. No apparent abnormality of the heart, lung, and kidney; 6. No HCV, HIV and syphilis infection; 7. Patients should sign the informed consent of this study.
Exclusion criteria
Exclusion criteria: 1. If preoperative liver function is Child C, it cannot tolerate conformal radiotherapy; 2. With evidence of extrahepatic metastasis; 3. With evidence of unstable angina pectoris, symptomatic congestive heart failure, severe arrhythmia, acute myocardial infarction within the last six months, prolonged QT interval (>450ms); 4. Malignant or metastatic tumor in other sites in last 5 years; 5. Patients can not be followed-up regularly; 6. Patients participating in other trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival;Recurrent rates and Survival rates in 1,2 year;Volume of bleeding; | — |
Secondary
| Measure | Time frame |
|---|---|
| radiographic parameters;Liver function afer hepatectom; | — |
Countries
China
Contacts
Public ContactChengshuqun
Outcome results
None listed