prospective and multicenter randomize control study for the analgesia effect of diluted ntrous oxide on burns and injury dressing pain

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-11001690

Enrollment

Unknown

Registered

2011-11-07

Start date

2011-10-14

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

burn and injury dressing pain

Interventions

routine practice group:routine practice

routine practice+oxygen:routine practice+oxygen

routine practice+diluted nitrous oxide:routine practice+diluted nitrous oxide

Eligibility

Sex/Gender

All

Age

5 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. The participants are voluntary and written consent obtained; 2. the patients' age rangefrom 5 to 65, either male or female; 3. In-patients sustained burns or other injury requiring dressing procedure with 1%-70% total body surface area(TBSA); 4. Burns or injured area not affecting the vital signs and digital pulse oximeter monitorring; 5. Conscious and can express pain severity by Changhai Pain Scale.

Exclusion criteria

Exclusion criteria: 1. abdominal distension or suspected bowel obstruction, air embolism, pneumothorax, decompression sickness, epitepsia, chronic obstuctive pulmonary disease and acute respiratory infection, pregnancy, severe inhalation injury; 2. severe drug depandancy and mental disorder; 3. pharmacotical or pathological pulmonary fiberosis; 4. disease involving ear, nose, laringus such as sinuses, middle ear, tympan graft and history of drug abuse; 5. Maxillofacial injuries.

Design outcomes

Primary

Measure	Time frame
VAS;	—

Countries

China

Contacts

Public ContactZhao Jijun

li_yuxiang@163.com+86 13918430851

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026