The Effect of a Chinese Herb Formula on Non-alcoholic Fatty Liver Disease

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-11001661

Enrollment

Unknown

Registered

2011-11-03

Start date

2007-01-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-alcoholic Fatty Liver Disease

Interventions

Chinese herb formula group:treated with the Chinese herb formula

placebo group:treated by placebo

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 40 Chinese subjects with NAFLD (criteria of Society of Hepatology, Chinese Medical Association, 2002.10), aged 18-65 will be recruited. Inclusion criteria are as follows: alcohol consumption less than 40g/week; liver/speen (L/S) ratio no more than 1 by CT scan.

Exclusion criteria

Exclusion criteria: Subjects will be excluded if they have any of the following: ALT more than twice the upper end of the normal range, viral hepatitis, total parenteral alimentation or secondary liver disease such as hepatocirrhosis, autoimmune hepatitis, metabolic liver disease or drug induced liver disease, severe cardiovascular or renal dysfunction. Subjects with diabetes (fasting glucose more than or equal to 7.0mmol/L or postprandial glucose more than or equal to 11.1mmol/L) will also be excluded. Subjects treated with statins will be excluded.

Design outcomes

Primary

Measure	Time frame
The CT value of liver and spleen, and the ratio of liver/spleen;BMI;liver function;lipid profile;NEFA;HOMA (glucose/insulin);	—

Secondary

Measure	Time frame
adiponectin;IL-6;hs-CRP;TNF-alpha;leptin;	—

Countries

China

Contacts

Public ContactWang Wenjian

wj6518@163.com+86 021 52888221

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026