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The treatment of insulin in combination with acarbose

A prospective, randomized, open-label study comparing efficacy, convenience and safety of pre-prandial insulin and prandial insulin in combination with acarbose in elderly patients with type 2 diabete

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-11001648
Enrollment
Unknown
Registered
2011-10-28
Start date
2007-10-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetese

Interventions

A:isophane protamine biosynthetic human Insulin 70/30 (Novo Nordisk) injected subcutaneously 30 minutes pre-meal plus acarbose (Bayer) 50mg, 1/noon
B:isophane protamine biosynthetic human Insulin 70/30 (Novo Nordisk) injected subcutaneously 30 minutes pre-meal plus acarbose (Bayer) 50mg, 3/day
C:isophane protamine biosynthetic human Insulin 70/30 (Novo Nordisk) injected immediately pre-meal plus acarbose (Bayer) 50mg, 3/day.

Sponsors

Department of Geriatrical Endocrinology, Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Type 2 diabetes diagnosed in accordance with WHO criteria 1999 more than six months, age>=60 years old; glycemic control is still not satisfied for having been using insulin therapy more than 3 months (fasting plasma glucose>=7mmol/l and/or 2-hour postprandial plasma glucose>=10mmol/l, and/or HbA1c>=6.5%).

Exclusion criteria

Exclusion criteria: patients with known cancer; patients allergic to insulin or acarbose; serious systemic disease, acute complications of diabetes within 6 months; patients with poor compliance, the researchers consider the patient is not suitable to participate in the observation or who will affect the results.

Design outcomes

Primary

MeasureTime frame
blood glucose;

Countries

China

Contacts

Public ContactLi Chunlin
lcl301301@gmail.com+86 13810921655

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026