FindTrial
Sign In

A comparision of the effects of omeprazole and famotidine on prophylaxis of stress-related ulcers in elective neurosurgery patients

A comparision of the effects of omeprazole and famotidine on prophylaxis of stress-related ulcers in elective neurosurgery patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-11001637
Enrollment
Unknown
Registered
2011-10-20
Start date
2011-11-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing elective neurosurgery

Interventions

control group:saline was given preoperatively
omeprazole group:omeprazole was given preoperatively
famotidine group:famotidine was given preoperatively

Sponsors

Department of Anesthesiology, West China Hospital, Sichuan University, China.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 18-60 years old, ASA I-II patients shedulded for elective intracranil tumor resection.

Exclusion criteria

Exclusion criteria: Patients with AVM, aneurysmal bleed, bleeding and coagulation disorders, hepatic and renal failure, a history of peptic ulcers, metabolic disease, and those on antiplatelet and anticoagulation therapy, or with a preoperative Glasgow coma scale of (GCS)<9, preoperative guaiac-positive gastric content, and those on ventilator after surgery, were excluded.

Design outcomes

Primary

MeasureTime frame
occurrence of ulce;—

Secondary

MeasureTime frame
biomarker;—

Countries

China

Contacts

Public ContactYu Li
biaojieli@tom.com+86 028 85423593

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026