The effects of dexmedetomidine premedication on propofol sedation and combined propofol with remifentanil anesthsia in Patients Undergoing laryngeal microsurgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-11001616

Enrollment

Unknown

Registered

2011-10-08

Start date

2011-05-31

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vocal cord polyp

Interventions

P:Pre-injection of saline before induction of anesthesia

D1:Pre-injection of 0.25ug/kg dexmedetomidine before induction of anesthesia

D2:Pre-injection of 0.5ug/kg dexmedetomidine before induction of anesthesia

D3:Pre-injection of 1.0ug/kg dexmedetomidine before induction of anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: The patient who are ASAI and ready for undergoing laryngeal microsurgery. At the same time the age of the patient must between 18 to 60 and the BMI must be less than 30.

Exclusion criteria

Exclusion criteria: The patient complicated with 1. Difficult intubation; 2. Hypertension; 3. Heart and lung disease; 4. Consumption of alpha 2 adrenergic agonist or Antagonist recently, will be excluded.

Design outcomes

Primary

Measure	Time frame
Narcotrend Index;heart rate;Target concentration of propofol;Blood Pressure;	—

Secondary

Measure	Time frame
Target concentration of remifentani;	—

Countries

China

Contacts

Public ContactXiangcai Ruan

xc_ruan@hotmail.com+86 13760710099

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026