type 2 diabetes mellitus
Conditions
Interventions
A:diabetes standard treatment and metformin ( 0.25g oral for 3 times one day)
B:diabetes standard treatment and placebo ( also 3 times one day)
Sponsors
Southwest Hospital, The Third Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Volunteers who can compliance the treatment and have signed the informed consent form prior to performance of study-related procedures; 2) Age from 18 years to 80 years; 3) A diagnosis of type 2 diabetes defined as: a previous physician diagnosis of type 2 diabetes as documented in the subject's clinical record or a new diagnosis of type 2 diabetes ( fasting blood glucose >=7.0 mmol/L or random blood glucose >=11.1 mmol/L accompanied by acute metabolic decompensation or 2 hour plasma glucose in a 75 gram oral glucose tolerance test >=11.1 mmol/L); 4) All the patient also have been diagnosed as chronic heart failure.
Exclusion criteria
Exclusion criteria: Patients who meet any of the following exclusion criteria will be excluded from the study: 1) acute diabetic complications, acute cardiovascular diseases, or acute cerebrovascular diseases; 2) subjects who are intolerance to metformin therapy, or are using metformin currently; 3) type 1 diabetes mellitus; 4) subjects who have been given reasonable treatment, but their heart failure still can be relieve; 5) subjects who have been or intend to do coronary artery bypass grafting, percutaneous coronary intervention or cardiac transplantation in 4 months; 6) severe comorbidities, such as HIV infection, cancer, serious infection, mezzo or severe anemia, severe renal or liver insufficiency; 7) those participating in another clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rehospitalisation because of heart failure;Rate of death; | — |
Secondary
| Measure | Time frame |
|---|---|
| left ventricular function;quality of life;glycosylated hemoglobin; | — |
Countries
China
Contacts
Public ContactQiang Xu
Outcome results
None listed