Effect of recovering vascular hyporeactivity and anti-shock of low-dose terlipressin complexing noradrenaline in severe shock and other severe illness

Regulation of direct communication between VEC and VSMC on vascualr reactivity in shock

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-11001583

Enrollment

Unknown

Registered

2011-09-15

Start date

2011-05-08

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

all kinds of clinical severe shock with refractory hypotension

Interventions

A:Cured with NE based on fluid resuscitation

B:Cured with NE based on fluid resuscitation complexing TP

C:Cured simultaneously with TP and NE based on fluid resuscitation

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: patient of severe shock with refractory hypotension

Exclusion criteria

Exclusion criteria: heart failure, intestinal obstruction,pregnancy

Design outcomes

Primary

Measure	Time frame
Consumption of blood vessel active drugs;Liver and kidney function, blood gas analysis and blood routine analysis;Arteriolar diameter and flow speed;Vital signs;	—

Secondary

Measure	Time frame
RHINOLUX;PICCO;	—

Countries

China

Contacts

Public ContactLiangming Liu

liuliangming2002@yahoo.com+86 02368757421

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026