locally recurrent nasopharyngeal carcinoma
Conditions
Interventions
Radiotherapy:Radiotherapy (intensity modulated) treatment
Endoscopic surgery:Endoscopic surgery
Sponsors
The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. all patients were pathologically diagnosedwith undifferentiated or differentiated, nonkeratinizing, locally recurrent NPC with the tumors confined to: 1) the nasopharyngealcavity (rT1); 2) the postnaris or nasal septum(rT2a); 3) the superficial parapharyngeal space (rT2b); or 4) thebase wall of the sphenoid sinus (T3). 2. Patients volunteered to participate in this study and signed informed consent?
Exclusion criteria
Exclusion criteria: 1. distant metastasis (screening measures: chest X-ray, bone scan); 2. heart, lung function or other physical factors can not be completed treatment; 3. Department of nasopharyngeal tumor invasion of the skull base, extensive destruction or skull base tumor surrounding the internal carotid artery; 4. significant history of mental illness; 5. also associated with other anti-cancer therapy (including anti-tumor immune therapy) or to participate in clinical trials by other interventions; 6. severe nasopharyngeal ulcers, necrosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2,3,5-year local control rate, disease-free survival, overall survival, complications, quality of life, cost; | — |
Countries
China
Contacts
Public ContactWeiping Wen
Otolaryngology Hospital of the First Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed