Efficacy and Safety of probiotics on prevention of child antibiotic-associated diarrhea

Effective of probiotics on preventing child antibiotic-associated diarrhea: a multicenter randomized blank-controlled study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-11001570

Enrollment

Unknown

Registered

2011-05-26

Start date

2011-05-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Antibiotic associated diarrhea

Interventions

1:Antibiotic therapy plus blank control

2:Antibiotic therapy plus probiotics

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 3 month to 3 years old; 2. Children with diagnosed pneumonia or Bronchiolitis and receiving hospitalized therapy; 3. Receiving anti-infectious treatment more than 2 days, regardless of class of anti-infection drug, administration delivery route, simple or combination therapy

Exclusion criteria

Exclusion criteria: 1. Current diarrhea or diarrhea within 15 days when entrance; 2. Children require treatment in ICU; 3. Children receiving long term of immunosuppressive agents; 4. Childre suffering from alimentary tract operation; 5. Children suffering from rheumatic heart disease or infective endocarditis; 6. Children with diagnosed malnutrtion; 7. Child received any probiotics preparation or supplementary food including probiotics in 15 days before entrance

Design outcomes

Primary

Measure	Time frame
Frequency of any diarrhea and AAD;	—

Secondary

Measure	Time frame
Accompanied symptom;Severity;Laboratory test;	—

Countries

China

Contacts

Public ContactYuejie ZHENG

yuejiez@sina.com+86 13510332369

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026