Heroin addiction
Conditions
Interventions
Intervention group:tyrosine, provided for 14 days continuously
Control group:glucose, provided for 14 days continuously
Sponsors
School of Public Health, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. abstinent heroin abusers; 2.released from compulsive isolation detoxification center or the centre for education through labor; 3. male; 4. age 18–55 years; 5. right handedness; 6. uncorrected vision was upwards of 1.0; 7. smoking cigarettes; 8. injecting heroin was the main method of drug using; 9. absence of neurological or psychiatric disorders; 10. absence of major internal disorders; 11. no current use of methadone; 12. no current psychotropic medication; 13. absence of substance abuse or dependence; 14. negative urine detection; 15. able and willing to provide signed informed consent; 16. without metal tooth or other metal material in the body.
Exclusion criteria
Exclusion criteria: do not meet the inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes of brain activation measured by fMRI;the Snaith–Hamilton Pleasure Scale;the Obsessive-Compulsive Drug Use Scale;the Desires for Drugs Questionnaire;the Profile of Mood State; | — |
Countries
China
Contacts
Public ContactZengzhen Wang
Outcome results
None listed