coronary artery disease
Conditions
Interventions
Two groups:INTELLiVENT-ASV ventilation mode, Adaptive-support ventilation mode versus Physician-led weaning
Sponsors
Dept. of Anesthesia and Intensive Care
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Haemodynamically stable patients aged over 18 years, receiving mechanical ventilation support after elective coronary arterial bypass grafting will be consecutively included. Written informed consent will be obtained from each patient before surgery.
Exclusion criteria
Exclusion criteria: Preoperative exclusion criteria: patients older than 80 years or younger than 18 years, acute or chronic obstructive pulmonary disease (primary indication for ventilation), and concomitant valvular and/or aortic surgeries, major organ failure (liver disease, renal failure), history of seizure or stoke are excluded preoperatively. Postoperative exclusion criteria: Severe early postoperative haemorrhage (chest tube drainage >500 ml/h), surgical complications needing reoperation, myocardial ischemia (ST-segment depression) lasting more than 30 min, postoperative cardiac failure necessitating high-dose inotropes or intra aortic balloon pump; refractory hypoxemia (ratio of arterial oxygen tension [PaO2] to fraction of inspired oxygen [FIO2] <150 mmHg)?
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of mechanical ventilation during intensive care unit stay;Frequency of manual setting during intensive care unit stay;Frequency of alarms during intensive care unit stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital length of stay during hostipal stay;Reintubation rate during intensive care unit stay;Tidal volume within 10 minutes after weaning;Respiratory ratr within 10 minutes after weanin; | — |
Countries
China
Contacts
Public ContactPui-Nga Patricia LEUNG
Outcome results
None listed