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The effect of dexmedetomidine on intravenous analgesia after caesarean section

The effect of dexmedetomidine on intravenous analgesia after caesarean section

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-11001442
Enrollment
Unknown
Registered
2011-07-24
Start date
2010-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obstetric analgesia

Interventions

Group 1:the parturients received 20ml intravenous normal saline (NS) after delivery of the fetus, and whose postoperative PCA included sulfentanyl only
Group 2:the parturients received 0.5 µg/kg intravenous dexmedetomidine, and whose PCA protocol was the same as group 1
Group 3:the parturients were treated in the same way as group II during operation and received intravenous dexmedetomidine after delivery of the fetus, and whose PCA included sulfentanyl+dexmedetomidi

Sponsors

Shanghai medical college of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: parturients aged 18 to 40 with a height of 155 to 170 cm, who requested for analgesia, who had no obstetrics-related risk factors or drug allergy, who had no history of surgery in the middle and lower abdomen, and who were easy to communicate with

Exclusion criteria

Exclusion criteria: parturients who had long histories of using narcotic analgesic agents or NSAIDs or tranquillizers, who had past histories of psychiatric disorders, whose preoperative heart rate (HR) was <50bpm or preoperative systolic blood pressure (SBP) was <100 mmHg with cardiac conduction or rhythmic abnormalities, and who had past histories of neuromuscular and endocrine diseases or allergic reactions.

Design outcomes

Primary

MeasureTime frame
VAS of pain;The total consumption of sulfentanyl;The launch time of lactation and the amount of lochia discharge within 3 h after operation;pain threshold and pain tolerance threshold;

Secondary

MeasureTime frame
Parturient’s satisfaction and serum cortisol level;

Countries

China

Contacts

Public ContactShaoqiang Huang
timrobbins71@163.com+86 13918210787

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 8, 2026