Skip to content

Rapid assessment of the optimal sedation depth and decision making in anesthesia induction in patients with potential difficult ventilation

Rapid assessment of the optimal sedation depth and decision making in anesthesia induction in patients with potential difficult ventilation

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-11001418
Enrollment
Unknown
Registered
2011-07-13
Start date
2011-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anesthesia

Interventions

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients ASA I-III, aged between 18-65y, match with one of the following six criteria, undergoing elective surgery with general anesthesia will be voluntarily enrolled in this prospective study: 1. Airway obstruction by Oral, oropharyngeal or hypopharygeal and trachea neoplasm or mass; 2. Airway obstruction by cervical neoplasm or mass; 3. Airway obstruction by tumor or mass in anterior mediastinum; 4. Patients with snoreing disease and Obstructive Sleep Apnea; 5. Patients with distortion or narrowing of the larynx or trachea by cervical trauma, burning, surgery and post-radiotherapy; 6. Patients with BMI>=30 and Mallampati grade III-IV and Thyroid cartilage to mentum distance <6.0cm.

Exclusion criteria

Exclusion criteria: 1. Normal lumenal transverse area of trachea is less than 1/3 of the original by intratracheal neoplasm, or external compression from tumor or mass around trachea; 2. Respiratory distress in the sitting position due to airway obstruction; 3. Patients complicated with respiratory diseases including pneumonia, asthma, chronic bronchitis, pulmonary emphysema et al; 4. Patients with a high risk of aspiration including intestinal obstruction, full stomach, esophageal reflux; 5. Patients with history or family history of malignant hyperthermia.

Design outcomes

Primary

MeasureTime frame
uccessful awake intubation rate;successful intubation rate after lossing consciousness;intubation failure rate;

Secondary

MeasureTime frame
perception of satisfaction for induction and intubation in anesthesiologist;vital sign alterations during anesthesia intubation and before and after intubation;incidence of postoperative sore throat and hoarseness;degree of recall and perception of satisfaction in patients;facial expression grading scale during laryngoscope exposure and intubation , coughing and gra reaction;intubation duration;

Countries

China

Contacts

Public ContactYunxia Zuo
zuoyunxiahxa@yahoo.com.cn+86 28 85423591

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 24, 2026