Effects of goal-directed fluid optimization in coronary heart disease patients patients undergoing non-cardic surgey

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-11001405

Enrollment

Unknown

Registered

2011-06-22

Start date

2011-04-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary heart disease

Interventions

Group A:Goal-directed fluid therapy (GDT) is a term used to describe the use of cardiac output or similar parameters to guide intravenous fluid.

Group B:Perioperative standard fluid regimens management

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. With informed consent signed; 2. Age 60-80 years; 3. Selectvie abdominal surgery under general anathesia; 4. Diagnosed with conronary heart disease; 5. Heart function I-III; 6. Hematocri t> 33%, hemoglobumin >110g/L.

Exclusion criteria

Exclusion criteria: 1. Pregnant women; 2. Psychiatric patients; 3. American Society of Anesthesiologists’(ASA) physical status IV, or any E group; 4. Significant renal or hepatic dysfunction; 5. Congestive heart failure or valvular heart disease; 6. Blood loss is<1000ml.

Design outcomes

Primary

Measure	Time frame
Incidence of adverse cardiac events after operation;Perioperative hemodynamic situation (Heart Rate, Mean Arterial Pressure, Cardiac output, Stroke Volum);The incidences of complications and mortality by Follow-up in the end of 3th month for survival;	—

Secondary

Measure	Time frame
Perioperative total of intraoperative fluids;	—

Countries

China

Contacts

Public ContactHong Zheng

xyzhenghong@yahoo.com.cn+86 13565996995

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026