Mild Cognitive Impairment and Pre-mild Cognitive Impairment
Conditions
Interventions
Two groups:For any week, at least 3 social groups of one hour duration should be arranged for the participants.
(to be continued):This will be a Single Blind Randomized Controlled Trial of 12 months duration. Chinese adults (aged 60 or above) with mild cognitive decline (Mild Cognitive Impairment [MCI] and pre-
(to be continued):The intervention groups comprised of cognitive (C), physical (P), cognitive-physical (CP) and social (S) programs. Each participant will participate in regular activities arranged by
Duration of intervention: One Year
(to be continued):1. The Social (S) group will serve as the controlled arm. Groups randomized as S would comprise of social activities selected. For any week, at least 3 social groups of one hour dura
(to be continued):For any week, at least 3 cognitive groups of one hour duration each should be arranged. 3. The Physical (P) group will have training on physical exercise. Groups randomized as P woul
(to be continued):4. The Cognitive-Physical (CP) group will have training on both physical exercise and cognitive activities. Groups assigned as CP would comprise of 2 types of cognitive activities wi
(to be continued):The
Sponsors
Simon KY Lee Fund for the Elderly
Eligibility
Sex/Gender
Male
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Subjects 60 years or above; 2. Satisfied criteria for MCI and pre-MCI by a cognitive screening package; 3. Physically fit with low risks of fall as assessed by the research team.
Exclusion criteria
Exclusion criteria: 1. Clinical dementia with a Clinical Dementia Rating, CDR >=1; 2. Already been prescribed with anti-dementia medication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Cognitive assessment included the list learning test, digit span, visual span, category verbal fluency (CVFT) and trail making tests. 2. Subjective cognitive complaints (SCC) were determined by the Memory Inventory for the Chinese (MIC). It is a 22 item questionnaire exploring subjective cognitive problems in everyday activities 3. Everyday functioning would be assessed by the Disability Assessment for Dementia (DAD), the validated Chinese version assesses both basic and instrumental act;Clinical Dementia Rating (CDR) sum of boxes scores. CDR is a semi-structured clinical interview for assessment of global cognitive ability. Six areas are assessed to give an overall rating of global cognition (0, not demented; 0.5, very mild dementia; 1 to 3, mild to severe dementia). The sum of boxes refers to summative scores of the six domains of everyday cognition and functioning measured in CDR (orientation, memory, judgment, habits and hobbies, self care and community activities). It is se; | — |
Countries
China
Contacts
Public ContactLinda CW Lam
Outcome results
None listed