Interventional treatment of benign airway stenosis with balloon catheter dilation, argon plasma coagulation, cryoablation and airway stents: a multi-center, randomized, open-label, controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-11001355

Enrollment

Unknown

Registered

2011-05-22

Start date

2011-05-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

benign airway stenosis

Interventions

Group A:Balloon dilation

Group B:Balloon dilation+argon plasma cogulation+cryo therapy

Group C:Balloon dilation+argon plasma cogulation

Group D:Airway stenting

Group E:Balloon dilation+cryo therapy

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Male and female aged 18 to 70 years old; 2. Able and willing to provide signed informed consent; 3. Benign airway stenosis without active tuberculosis; 4. Pedicted survival time>3 months; 5. Recieved no intra-tracheal procedures in one months before this study.

Exclusion criteria

Exclusion criteria: 1. Patients who is in severe condition unable to be bronchoscoped; 2. Recieveing mediastinum radiation therapy; 3. Unstable bronchial tuberculosis.

Design outcomes

Primary

Measure	Time frame
response rate;Overall survival, OS;Time to Progression, TTP;Median Survival Time, MST;complete response rate;clinical benefit rat;	—

Secondary

Measure	Time frame
Karnofski performance score;dyspnea index;	—

Countries

China

Contacts

Public ContactHongwu Wang

wanghongwu2003@yahoo.com.cn+86 10 64685688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026