advanced gastric cancer
Conditions
Interventions
A:Traditional open surgery
Sponsors
Union Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Preoperative endoscopy and biopsy confirmed gastric adenocarcinoma; 2. Primary tumor resectable; 3. With gastric cancer that can be treated with radical resection: cTNM II-III A defined in 7th edition UICC / AJCC; 4. Age between 18 and 75 Years old, male or female, life expectancy >=12 weeks, BMI <=30 kg/m2 (medium or slim body), without other severe diseases; 5. WHO performance status <2; 6. Informed consent obtained from patients or their appointed agent.
Exclusion criteria
Exclusion criteria: 1. Patients with other gastric malignant diseases, such as lymphoma and stromal tumors, etc.; 2. Patients suffering from malignant diseases before the study; 3. With other severe comorbidities and cannot tolerate laopen surgery can not tolerate laparoscopic surgery or open surgery: such as severe heart and lung diseases, heart function below clinical stage 2, pulmonary infection, moderate to severe COPD, chronic bronchitis, severe diabetes and / or renal insufficiency, severe hepatitis and / or function below the rank of CHILD B grade, and severe malnutrition, etc; 4. Patients with previous history of upper abdominal surgery; 5. Patient undergo emergency surgery due to bleeding or perforation of gastric cancer; 6. Patients treated with neoadjuvant chemotherapy or radiation therapy which might affect the efficacy observation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain;3 and 5-year survival rate;Quality of Life;Compliance rate of lymph node dissection;Operative mortality;Negative rate of tumor margins, The length of cut-s;Complications;Operation time;Intestinal recovery exhaust time;The number of lymph node dissection;Postoperative stress;Immune response;Blood loss; | — |
Countries
China
Contacts
Public ContactChangming HUANG
Outcome results
None listed