anesthesia
Conditions
Interventions
Group C:patients were epidurally administered with 0.15 ml
Group IV:patients were intravenously injected with 2mg/kg
Group TEA:patients were epidurally administered with 0.15 ml/kg of lidocaine 1.35% in the T5-6 vertebral interspace.Fifteen minutes after the injection, the upper and lower levels of loss of cold and
Sponsors
Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
22 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. ASA physical status I and II; 2. Male and female aged 22 to 60 years old, BW48-80kg; 3. scheduled for thoracic surgery.
Exclusion criteria
Exclusion criteria: 1. Drug abuse, mental illness historyand obesity( >IBW 130%); 2. patients with cardiovascular or neurological disease and Unstable hypertension; 3. Communication disorders; 4. Contraindication with propofol, opioids and lidocaine; 5. Tobacco and alcohol addiction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| plasma concentration of norepinephrine;BIS score;the plasma concentration (Cpt) and the effect-site concentration of propofol TCI;mean arterial pressure;plasma concentration of cortisol;plasma concentration of epinephrin; | — |
Secondary
| Measure | Time frame |
|---|---|
| plasma concentration of lidocaine;loss of consciousness time;Heart rate; | — |
Countries
China
Contacts
Public ContactWenzhi Li
Outcome results
None listed