Chronic liver diseases and liver cirrhosis
Conditions
Interventions
TUDCA group:TUDCA 250mg po Bid
Control group:No TUDCA
Sponsors
Guangdong Province Sci-tech Department
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The informed consent signed; 2. Aged 18-65 years old; 3. Non-heart beating liver transplant recipients
Exclusion criteria
Exclusion criteria: 1. Pregnant or breast-feeding women; 2. Severe cardiac or renal dysfunction; 3. Severe endocrinological, hematic or mental diseases; 4. Acute gastric or duodenal ulcer; 5. ABO blood type incompatibility; 6. Cold ischemia time of allograft longer than 12 hours or warm ischemia time longer than 15 mins; 7. Death due to known reason within one week post-tranplantation; 8. Follow-up not conducted in the institute of transplantation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| biliary complications, such as bile leakage, bile duct stricture and biliary sludge;acute rejection episodes;allograft loss;early allograft dysfunction;death of recipients; | — |
Secondary
| Measure | Time frame |
|---|---|
| The time for Tbil, GGT and ALP to drop within normal range and the range of dropping in one month po;The time for AST and ALT to drop within normal range and the range of dropping in one month post-tra; | — |
Countries
China
Contacts
Public ContactXiaoshun HE
Outcome results
None listed