Hemorrhagic shock in pregnant women
Conditions
Interventions
PLS:Second stage: restricted isotonic saline + colloid fluid administrated intravenously in pre-hospital resuscitation to maintain the MAP in optimal range.
PLH:Second stage: restricted isotonic saline + hypertonic solution chloride hydroxyethyl starch 40 administrated intravenously in pre-hospital resuscitation to maintain the MAP in optimal range
PLS60:First stage: restricted fluid administration in pre-hospital resuscitation to maintain MAP within 60-70 mmHg
PNL:First stage: restricted fluid administration in pre-hospital resuscitation to maintain MAP over 70 mmHg
PLS50:First stage: restricted fluid administration in pre-hospital resuscitation to maintain MAP within 50-60 mmHg
Sponsors
Southern Medical University nanfang hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Aged 20-40 yrs; 2. Patients with mild to moderate hemorrhagic shock followed by rupture of ectopic pregnancy or delivery (first systolic pressure<90 mmHg), and with active bleeding before stanching bleeding; 3. Hemorrhagic shock is due to explicit obstetric cause; 4. Patients voluntarily signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with complication of pregnancy; 2. Patients with history of chronic disease; 3. The bleeding is due to coagulation disorder or amniotic fluid embolism; 4. The first mean arterial pressure<50mmHg.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood loss volume;Mortality;Transfusion volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound healing;Incidence of hysterectomy, MODS or ARF;Total expense of hospitalization;Total in-hospital day; | — |
Countries
China
Contacts
Public ContactYanhong Yu
Outcome results
None listed