ankylosing spondylitis
Conditions
Interventions
B group:Qiangji Granule placebo, Sulfasalazine, Ibuprofen
C group:Qiangji Granule placebo, Sulfasalazine, Ibuprofen
Sponsors
School of Chinese Medicine Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients 18 to 60 years of age and who had AS according to the modified 1984 New York Criteria for AS; 2. active disease defined by a Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) score of at least 4; 3. both male and female; 4. the patients with ankylosing spondylitis with Gan-shen deficiency and Moist Heat Arthralgia Spasm Syndrome type; 5. Signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. 4 weeks before the start of this study had participated in others clinical trials; 2. Pregnant women or lactating women; 3. Who can not be tolerated drug during the course of the study; 4. server primary disease in cardiovascular, cerebrovascular, liver, kidney and hemopoietic system; 5. severe joint deformities, loss of function in patients with ankylosing spondylitis; 6. patients who with seronegative spondy loarthropathies, or complicating with other rheumatic; 7. the psychiatric patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BASDAI;ASQoL;BAS-G;BASFI;ASAS20;BASMI;DFI;HAQ-S; | — |
Secondary
| Measure | Time frame |
|---|---|
| tragus-to-wall distance;Modified Schober's test;Finger-to-floor distance;erythrocyte sedimentation rate;morning stiffness;Occiput-to-wall distance;Patrick's test;chest expansion;lumbar side flexion;C-reactive protein; | — |
Countries
China
Contacts
Public ContactLi Yi-kai
Outcome results
None listed