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Study on clinical evaluation of treating severe traumatic brain injury by pricking blood on twelve hand well points and combined nasal coixenolide with mild hypothermia

Study on clinical evaluation of treating severe traumatic brain injury by pricking blood on twelve hand well points and combined nasal coixenolide with mild hypothermia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-11001226
Enrollment
Unknown
Registered
2011-01-05
Start date
2011-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe traumatic brain injury

Interventions

Group A:Mild hypothemia and nasal feeding of coix granules
Group B:Mild hypothermia therapy
Group C:Mild hypothemia and pricking blood on well points
Group D:Combined mild hypothemia with nasal feeding of coix granules and pricking blood on well points

Sponsors

Tianjin University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Have a clear history of head injury; 2. Head CT scans show brain damage;coma more than 6 hours after injury, or show awareness of deterioration within 24 hours after injury ,and coma again for more than 6 hours; 3. GCS score: ranged from 3 to 8; 4. Admitted to hospital within 24 hours after injury; 5. Age of 15-65 years old.

Exclusion criteria

Exclusion criteria: 1. Patients with acute severe traumatic brain injury associated with serious injury of other organs; 2. Dysfunction of cardiopulmonary,liver and kidney etc.; 3. Pregnant and lactating women; 4. the one who is considered unfit to inclusion criteria by the doctor.

Design outcomes

Primary

MeasureTime frame
Neural body scale;TCM syndrome differentiation table;evoked potential;Pittsburgh brainstem score;EEG;GCS score;vant indicators of brain function;

Secondary

MeasureTime frame
GOS score;Severe cranial trauma;

Countries

China

Contacts

Public ContactXingfang Pan
panxingfang1969@hotmail.com+86 13502009611

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026