chronic discoid lupus erythematosus and oral lichen planus.
Conditions
Interventions
Group A:Triamcinolone Acetonide Acetate Ointment the first week three times aday
the seconed week two times a day
the third week one times a day
Group B:Tacrolimus 0.03% ointment, the first week three times aday
Sponsors
West China College of Stomatology, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-60 years old; 2. Subject decided independently to participate in the study and sign informed consent; 3. Histopathologically and clinically proved erosive OLP/CDLE and have labial lesions; 4. The lesion size exceeding 5 mm in diameter; 5. Disease-process exceeding 2 months; 6. Negative reaction to pregnancy test in women.
Exclusion criteria
Exclusion criteria: 1. History of allergies to dexamethasone or a known history of serious drug hypersensitivities; 2. Those with other severe oral mucous diseases; 3. Those taking immunopotentiating or immunosuppressive agents during the previous 3 months; those having topical treatment within a week; 4. Have dieases with SLE; 5. Those with severe systemic diseases or abnormal hepatic or renal function test; a history of hepatitis C; 6. Pregnancy or intention of pregnancy or lactation or use of contraceptives of steroid hormone recently; 7. History of psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lesion size, pain level; | — |
Countries
China
Contacts
Public ContactHongmei Zhou
Outcome results
None listed