Stable Angina
Conditions
Interventions
Low dose group:Ginseng total sub-glycosides orally disintegrating tablet (0.35g / piece, Ginseng total sub-glycosides containing about 37mg / piece), the mouth sublingual 3 times a day, Once a piece
the Placebo oral disintegrating tablets, oral sublingual 3 times a day, Once a piece for 8 weeks.
High dose group:Ginseng total sub-glycosides orally disintegrating tablet (0.35g / piece, Ginseng total sub-glycosides containing about 37mg / piece), the mouth sublingual 3 times a day, Once 2 piece
Placebo group:The Placebo oral disintegrating tablets, oral sublingual 3 times a day, Once 2 piece for 8 weeks.
Sponsors
Guangdong Provincial Hospital of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Age 18 to 65 years; (2) Classification of angina severity was grade II-III; (3) Angina attack can use the available nitrates mitigation; (4) To complete the ECG exercise stress test, and positive test results; (5) Informed consent, and written informed consent.
Exclusion criteria
Exclusion criteria: (1) Occurred within 3 months of Myocardial Infarction or history of Unstable Angina, or had coronary revascularization (Bypass surgery or Angioplasty); (2) Combined with other heart disease, neurosis, menopausal syndrome, hyperthyroidism, cervical disease, Biliary-cardiac syndrome, stomach - esophageal reflux disease or Esophageal hiatal hernia and other diseases may cause chest pain; (3) The following abnormalities of resting ECG: complete left bundle branch block, preexcitation syndrome, ventricular pacing rhythm, ST segment depression more than 0.1mv or left ventricular hypertrophy; (4) Merger of uncontrolled or symptomatic heart failure or echocardiography prompted left ventricular ejection fraction = 2 times the upper limit of normal reference values; (8) Abnormal renal function (serum creatinine> upper limit of normal reference values.); (9) Complicating the respiratory system, hematopoietic system or malignant tumor and severe primary disease; (10) Pregnant women, lactating womenor women of child-bearing age have fertility requirements; (11) Mental illness, or cognitive dysfunction; (12) The expected patients who are poor compliance, lack of regular visits, or can not be completed in accordance with the requirements of a doctor patient diary cards; (13) Within the last 3 months have participated in other clinical trials or have received this randomized clinical trial; (14) The researchers perceived there is not suitable to participate in the trial of other cases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treadmill test standard; | — |
Secondary
| Measure | Time frame |
|---|---|
| Echocardiography;Standards of TCM symptoms;ECG standard;Angina episodes; | — |
Countries
China
Contacts
Public ContactHuanlin Wu
Outcome results
None listed