Herpes Zoster, Post-Herpetic Neuralgia
Conditions
Interventions
ST:standard pharmacological treatment
Sponsors
Institutional funds from Regione Abruzzo were delivered to Fondazione Onlus Camillo de Lellis per l’Innovazione e la Ricerca in Medicina, Pescara, Italy
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Patients with confirmed diagnosis of Herpes Zoster enrolled in the parallel cohort of Pescara VZV study (Parruti et al., Predictors ofpain intensity and persistence in a prospective Italian cohort of patients with herpes zoster: relevance of smoking, trauma and antiviral therapy. BMC Med. 2010 Oct 11;8:58);2. Patients with pain classified as intense or very intense on a five-degree semi-quantitative scale
Exclusion criteria
Exclusion criteria: 1. Patients with mild or moderate pain at presentation; 2. Patients unwilling or unable to provide signed informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the reduction in pain intensity between baseline and the end of the 4-week treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| the total pain burden during the 12-month follow-up of the cohort study;the response rate (VAS score decrease by at least 2 points during treatment);the reduction in the score of the McGill Pain Questionnaire (MPQ);the percentage of incident cases of PHN;the incidence of treatment-related serious adverse events during treatment; | — |
Countries
Italy
Contacts
Public ContactGiustino Parruti
Outcome results
None listed