Acute primary supratentorial intracerebral hemorrhage
Conditions
Interventions
Control group:Placebo+conventional medical treatment
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age from 18 to 80 years; 2. Acute spontaneous supratentorial ICH; 3. Haematoma volume between 10 to 30ml; 4. GCS score>8; 5. Admission within 24 hours of ictus.
Exclusion criteria
Exclusion criteria: 1. The haemorrhage was probably due to an aneurysm or an angiographically proven intracranial vascular malformation or tumour stroke; 2. Associated with head injury or traumatic history; 3. Patients with mutiple intracerebral hemorrhage; 4. Patients who had severe pre-existing physical and/or mental disability; 5. Coagulation disorders or history of anticoagulant; 6. History of gastric ulcer or diabetes mellitus ; 7. Hypoimmunity or infection; 8. Patients who have reveived long-term glucocorticord treatment; 9. Patients who received drugs which may influnce blood sugar, immunity, gastrointestinal function or the methylprednisolone metabolism 1month prior to the enrollment; 10. Hepatic and/or renal dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Edema aroud the hematoma, Mortality, GOS score, Modified Rankin Scale, NIHSS Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hepatic and renal function, electrolyte, size of hematoma, vital indications; | — |
Countries
China
Contacts
Public ContactChao You, Ming Liu
Outcome results
None listed