colorectal cancer
Conditions
Interventions
B:Open surgery
A:HALS surgery
Sponsors
Beijing Cancer Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Pathological diagnosis of colorectal cancer; 2. Resectable sigmoid colon cancer or upper rectum cancer; 3. Clinical staging lower than 4a; 4. no radiological metastasis; 5. No previous gastrointestinal surgery; 6. No pre-operative radiotherapy; 7. Without complete bowel obstruction; 8. good cardiopulmnoary functions; 9. Karnofsky score more than 70; 10. signature of informed consent; 11. Female patients in trails must under contraception. And patients who is menopause should be assureed for 12 months and pregnancy should be ruled out; 12. No other relevant diseases (tumors in other sites or serious disease heart or central nervous system, CNS); 13. WBC > 3.5*10^9/ml, PLT> 10*10^9/ml, T-Bil 50ml/min.
Exclusion criteria
Exclusion criteria: 1. uncontroled underlying diseases (unstable angina etc); 2. Previous history of immunosuppresive therapy (including corticosteroids therapy); 3. pre-operative radiotheraphy; 4. preexciting metastasis; 5. attending other relative clinial trials; 6. difficulty in endure anesthesia and surgery; 7. serious uncontroled infection; 8. Diseases of CNS or psyche which affect congnition including CNS metastasis; 9. Serious allergy history; 10. Serious pulmonary heart disease; 11. Female of pregnant and lactation or patients who reject contraceptional therapy during treatment period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OS;Surgical complication; | — |
Countries
China
Contacts
Public ContactJin Gu
Outcome results
None listed