Arthroscopic anterior cruciate ligament reconstruction surgery of knee joint
Conditions
Interventions
Two groups:Intra-articular injection of magnesium for post-operative pain control versus placebo
Sponsors
Department of Anaesthesia and Intensive Care, CUHK
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adult patients of ASA I-II and mentally capable for informed consent, who are scheduled for elective arthroscopic ACL reconstruction will be recruited in the study
Exclusion criteria
Exclusion criteria: 1. ASA III or above; 2. Impaired renal or liver function ?History of chronic pain or substance abuse ?Known hypersensitivity to sulphur drug or NSAIDs; 3. Contraindicated for NSAIDs, such as known hypersensitivity, past history of peptic ulcer disease or platelet dysfunction; 4. Pregnancy or lactation in female patients; 5. Contraindications for administration of MgSO4, such as heart block, myocardial damage, myopathy or neurological disorders; 6. Concomitant medications: digitalis, calcium channel blocker, central nervous system depressants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score at rest. on movement and on weight bearing; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation, muscle weakness and magnesium level.; | — |
Countries
China
Contacts
Public ContactDr Chan, Simon Kin Cheong
Outcome results
None listed