Randomized double-blind investigation of glycopyrrolate as an adjunct to phenylephrine for maintenance of maternal blood pressure during spinal anaesthesia for Caesarean section

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-10001097

Enrollment

Unknown

Registered

2010-12-01

Start date

2010-11-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy

Interventions

Two groups:Glycopyrrolate versus placebo

Eligibility

Sex/Gender

Male

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists Physical Status 1 or 2 normotensive non-labouring parturients with term singleton pregnancies who are scheduled for elective Caesarean section and who have been judged suitable and have agreed to have for spinal anaesthesia according to usual clinical criteria

Exclusion criteria

Exclusion criteria: Known fetal abnormality, preexisting or pregnancy-induced hypertension, known cardiovascular or cerebrovascular disease, thrombocytopaenia, coagulopathy, or any medical contraindication to spinal anaesthesia, weight 100 kg, height 180 cm, inability to give informed consent

Design outcomes

Primary

Measure	Time frame
Maternal cardiac output 5 min after induction of spinal anaesthesia;	—

Secondary

Measure	Time frame
Blood pressure and heart rate changes from induction of spinal anaesthesia until uterine incision;	—

Countries

China

Contacts

Public ContactProf Warwick D. Ngan Kee

warwick@cuhk.edu.hk+852 26322735

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026