Rat nerve growth factor injection in the treatment of children with spinal muscular atrophy: a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-10001093

Enrollment

Unknown

Registered

2010-11-02

Start date

2010-10-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

children with spinal muscular atrophy

Interventions

A:Rat nerve growth factor injection for six monthes,

B:Rat nerve growth factor injection for six monthes,

Eligibility

Sex/Gender

All

Age

3 Years to 8 Years

Inclusion criteria

Inclusion criteria: 1. Male or female aged 3~8 yrs; 2. Children with spinal muscular atrophy, diagnosed based upon the standard of the World Federation of Neurology (1994 version); 3. To be firstly diagnosed as type SMA II, did not use any rat nerve growth factor in last 6 months; 4. To be changed in the electromyogram (EMG); 5. Had signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Who is attending another trial, or to be attended other trials in last month; 2. Who is treated by other drugs; 3. Severe liver or kideny disease, blood system disease, authoimmunity disease, chronic severe infections, etc; 4. Who unable to complete the nine monthes period follow-up; 5. Other reason the researcher considered not suite for research.

Design outcomes

Primary

Measure	Time frame
Pediatric Evaluation of Disability Inventory (PEDI);	—

Secondary

Measure	Time frame
Electromyogram presentation;	—

Countries

China

Contacts

Public ContactZhou Liping

zouliping21@hotmail.com+86 10 66939770

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026