Influence of multimodal analgesia with parecoxib and morphine on post surgical delirium in elderly patients

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-10001063

Enrollment

Unknown

Registered

2010-10-28

Start date

2010-12-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative analgesia and delirium

Interventions

A:multimodal analgesia with parecoxib and morphine PCA

B:opioids PCA

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: Age >=60 years; intends to elective non-cardiac surgery

Exclusion criteria

Exclusion criteria: 1. The patients who refuse to participate this clinical trail and can not communicate with others in mandarin; 2. Any known allergy / forbidden to sulfonamides or opioids; 3. Severe hepatic impairment or renal insufficiency; 4. Acute peptic ulceration, nerve system diseases; 5. Mental disorder; 6. Congestive heart failure and severe coronary heart disease; 7. Operative time 6 hours; 8. ASA>III; 9. Who was enrolled in other trials simultaneously; 10. For other exclusion reasons diagnosed by researchers.

Design outcomes

Primary

Measure	Time frame
Pain at rest and pain with movement are assess at 6, 24, 48, 72hours after surgery;Dilirium diagnosis with CAM-ICU from 1 to 7 days after operation, twice per day (8-10am, 4-5pm);	—

Secondary

Measure	Time frame
Servival rate 28 days after operation;Dilirium rate;Adverse events after operation;	—

Countries

China

Contacts

Public ContactZhen Hua

hua1013@163.com+86 13311398620

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026