Randomized, Multicenter, Parallelcontrol study on evaluation for the clinical effectiveness of Angong Niuhuang Boluses against Stroke with phlegmy heat symptom-complex

Research of Key Techniques on Evaluation for the clinical effectiveness of chinese herbal medicine which can take the advantage on the effectiveness of traditional chinese medicine

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-10001016

Enrollment

Unknown

Registered

2010-09-22

Start date

2010-10-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke

Interventions

Group A:Basic therapy + Angong Niuhuang Boluses

Group B:Basic therapy

Eligibility

Sex/Gender

All

Age

35 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients who present within ischemic stroke whithin 48 hours; 2. Age between 35 and 80; 3. Suitable for the the syndrome diagnosis of phlegmy syndrome and heat syndrome through "Ischemic Stroke TCM Syndrome Factor Diagnostic Scale" (ISTSFDS) or the syndrome diagnosis of yang block syndrome of Stoke of Bowel and viscerae, are eligible for this study; 4. National Institute of Health Stroke Scale (NIHSS) scores >5.

Exclusion criteria

Exclusion criteria: 1. Patients who receive treatment of ischemic stroke by thrombolysis in Ultra-early stage; 2. Complicated with hepatic, kidney, hematological, endocrine, osteoarthropathy disease, mental disorder, serious dementia or sequela of apoplexy; 3. Transient ischemic attack, intracranial hemorrhage or subarachnoid hemorrhage; 4. Rheumatic heart disease,coronary heart disease or other heart diseases complicated by atrial fibrillation disease; 5. Brain tumor, brain trauma and hematological diseases result in cerebral embolism.

Design outcomes

Primary

Measure	Time frame
Modified rankin scale Score of stroke 90th day;"Ischemic Stroke TCM Syndrome Factor Diagnostic at day 14 of onset the stroke;NIHSS score of stroke 14th day;	—

Secondary

Measure	Time frame
BI score of stroke on the 90th day after onset;	—

Countries

China

Contacts

Public ContactGaoYing

gaoying973@126.com+86 10 84013209

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026