Opioid drug addiction
Conditions
Interventions
Sponsors
Neuroscience Research Institute, Peking University
Eligibility
Sex/Gender
Male
Age
22 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Aged from 18 to 55, male; 2. In accordance with the diagnostic standards of DSM-IV & ICD-10 for addicted and DSM-IV for abstinence; 3. Qualitative urine detection for opioids showing positive result; 4. Cleared for 8 to 36 hours after their last drug taking; 5. Fully understood and signed on informed consent.
Exclusion criteria
Exclusion criteria: 1. Person with consciousness disorder on opioid abstinence, seriously aggressive, heavily dehydrated and intending to commit suicide; 2. Patients with serious liver and kidney dysfunction, pulmonary decompensation, or complicated with serious damage in other systems; 3. Patients with serious infectious disease; 4. Patients with history of serious neurological or psychiatrical diseases; 5. Person with history of HIV infection or serious malnutrition; 6. Dependent upon and addicted to multiple drugs; 7. Attended some other drug trials within one month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anorexia scoring;Sweating scoring;Bellyache and diarrhea scoring;Overall scoring on withdrawal symptoms;Dose of buprenorphin;Impulsive behavior scoring;Insomnia scoring;Yawning scoring;Chilling scoring;Anxiety scoring;Musculo-skeletal pain scoring;Rhinorrhea scoring; | — |
Secondary
| Measure | Time frame |
|---|---|
| Spontaneous ejaculation scoring; | — |
Countries
China
Contacts
Public ContactJisheng Han
Outcome results
None listed