A Randomized Study Comparing Double Kissing Double Crush With PRovisional Stenting Techniques Using Polymer-free, adjustable dosage of Sirolimus-and Probucol-eluting Stents for Patients with Coronary Bifurcation Lesions: DKCRUSH-Plus trial

A Randomized Study Comparing Double Kissing Double Crush With Provisional Stenting Techniques Using Different Dosage and Polymer-free Sirolimus-eluting Yukon Stents for Patients with Coronary Bifurcation Lesions: DKCRUSH-Plus trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-10000965

Enrollment

Unknown

Registered

2010-08-05

Start date

2010-08-15

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary bifurcation lesion

Interventions

DK-1 group:Using DK crush technique Implants stents in MV have 2.5% Sirolimus and 1% probucol,stent in SB had 3% sirolimus and 1% probocol.

DK-2 group:Using DK crush technique Implants stents in MV have 2.5% Sirolimus and 1% probucol, stent in SB had 3% sirolimus only

PS group:Using DK crush technique,stents in MV having 2.5% Sirolimus and 1% probucol.If additional stent being required in side branch, this stent having 3% sirolimus only

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Documented silent ischemia, angina and AMI >72h; 2. Age 18-80years; 3. MV/SB size>=2.5mm, diameter stenosis>=50% by visual estimation; 4. Medina Classification-0, 1, 1; 1, 1, 1; 1, 0, 1; 5. Only one bifurcation lesion per vessel; 6. Bifurcation lesions after successful recanalization of chronic total occlusion in MV and/or SB (meet the other inclusion criteria); 7. Lesion length in MV/SB could be fully covered by 2 stents.

Exclusion criteria

Exclusion criteria: 1. Age >80 years; 2. Acute myocardial infarction2.5mg/dl; 6. Bleeding stroke within 6 months; 7. Left ventricular ejection fraction=2 bifurcation lesion in same vessel; 13. Medina Classification-1,0,0; 1,1,0; 0,1,0; 0,0,1.

Design outcomes

Primary

Measure	Time frame
Net gain;Major adverse cardiac events;	—

Secondary

Measure	Time frame
Coronary aneurysm;Late lumen loss;Angiographic restenosis;	—

Countries

China

Contacts

Public ContactShao-Liang Chen

chmengx@126.com+86 25 52208048

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026