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Comparison of therapeutic efficacy of topical corticosteroid and oral zinc sulfate-topical corticosteroid combination in the treatment of vitiligo patients: a randomized clinical trial

vitiligo and zinc

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-10000930
Enrollment
Unknown
Registered
2010-06-24
Start date
2007-01-12
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitiligo

Interventions

A:topical corticosteroid as 0.05% clobetasol propionate cream in isopropyl alcohol 65o preparation (in equal proportion) for the body and 0.1% triamcinolone acetonide cream for the face and flexures,
B:topical corticosteroid (compatible with the first group) admixed with oral zinc sulfate (220-mg capsule) in dose of 2 capsules per day in teenager and adults and 10mg/kg of capsule or syrup for chil
. For the second group, serum zinc level was repeatedly measured 1 and 3 months after commencing the treatment.

Sponsors

Jundishapour University of Medical Sciences, Ahvaz, Iran
Lead Sponsor

Eligibility

Sex/Gender
All
Age
11 Years to 59 Years

Inclusion criteria

Inclusion criteria: Any ageAny gender The localized and gneralized types of vitiligo with exception of segmental one (with involvement <20% of body surface)Vitiligo duration less than 5 yearsNegative history of systemic disorderNo pregnancyNegative history of drug administrationNormal or low serum zincNormal other laboratory testsTaking no zinc during 4 weeks prior to referring

Exclusion criteria

Exclusion criteria: The segmental and universal types of vitiligo Positve history of systemic disorder Pregnancy Positive history of drug administration High serum zinc Abnormal other laboratory tests Taking zinc during 4 weeks prior to referring

Design outcomes

Primary

MeasureTime frame
Physical Examination;Vitiligo data;The results of treatment;Past history;Demographic data;Data of the two study groups;Laboratory test;

Countries

Iran

Contacts

Public ContactReza Yaghoobi
yaghoobi_rz@yahoo.com+98 0916 1186021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026