primary glaucoma
Conditions
Interventions
A:Intensive regulation: standard trabeculectomy + intraoperative IOP control by manipulatoin of sutures
B:Control: standard trabeculectomy
Sponsors
Beijing Tongren Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients are diagnosed as primary open-angle glaucoma(POAG) or primay angle-closure glaucoma(PACG): glaucomatous optical nerve damage (such as narrowed optic disc edge, edge incisure, nerve fiber layer defect) and the corresponding repeatable visual field defect (GHT shows three consecutive relative scotomas (p=21mmHg; 3. Aged between 18 and 80 years old; 4. Patients who is going to receive initial trabeculectomy; 5. Written informed consent obtained.
Exclusion criteria
Exclusion criteria: 1. Secondary glaucoma (such as neovascular glaucoma , uveitis, external injury, lens expansion and etc.) or acute angle-closure glaucoma (including patients with past history of acute onset or definite onset signs); 2. Trabeculectomy combined with other procedures; 3. Patients having used systemic and local agents which may affect IOP for a long duration; 4. Patients having received the conjunctiva and intraocular surgeries; 5. Severe systemic diseases (such as stroke, tumor and etc.) that may affect follow-up plan or potentiality of moving to other areas in 6 months; 6. Patients with single eye; 7. Patients who are unable or unwilling to accept the long-term follow-up according to the project requirements; 8. Patients refusing to sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of IOP control;Intraocular pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of postoperative complications;The grading of the filtering bleb;The incidence of postoperative intervention; | — |
Countries
China
Contacts
Public ContactYuanbo LIANG
Outcome results
None listed