surgery related diseases
Conditions
Interventions
Group A:General anesthesia will be induced with midazolam, fentanyl, scoline and propofol, and maintained with remifentanil, atracurium, propofol.
Group B:Anesthesia will be induced using the same protocol as that in the control group, but maintained with remifentanil and propofol.
Sponsors
The First Hospital of Lanzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged from 18 to 80 years old with preoperative ASA grade I or II; 2. Undergoing a non-abdominal operation using general anesthesia; 3. No history of drug addiction, central or peripheral nervous system pathology, vegetarian nervous disorders or nerve-muscle adaptor lesions. No history of autoimmune diseases or familial genetic diseases; 4. Agreed to participate in orally before operation or sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Unwilling to participate in or refuse to sign an informed consent form; 2. Patients with blood loss more than 30% of total blood volume during operation, or with anemia (Hb lower than 90 g/L) ; 3. Hypotention(sBP<12 Kpa) persist more than 5 min, hypoxia (SpO2<=90%) persist more than 30 seconds or pernicious arrhythmia, cardiac arrest or other unexpected accidents occur during operations; 4. Patients be found allergy to anesthetics, or have family history of malignant hyperthermia; 5. Operations are affected by muscle tension, body movement or other circumstances.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recovery time, body movement;BIS,TOF;MAP, HR, SPO2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anesthetics dosage, anesthesia expense; | — |
Countries
China
Contacts
Public ContactYulan Li
Outcome results
None listed