The Preventive Effect of Continuous Atomization Inhalation on the Reintubation in Abdominal Surgery Patients with Mechanical Ventilation

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-10000839

Enrollment

Unknown

Registered

2010-04-14

Start date

2010-03-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal Surgery Patients with Mechanical Ventilation

Interventions

case group A:Ambroxol Hydrochloride, 90mg+Ipratropium Bromide,12ml+sterilized water for injection,500ml continuous atomization Inhalation for 48h, then take the measure as control group

case group B:5% of sodium bicarbonate solution, 250ml+ physiological saline solution, 250ml continuous atomization Inhalation for 48h, then take the measure as control group

control group:Ambroxol Hydrochloride,15mg+Ipratropium Bromide, 2ml+sterilized water for injection, 5ml discontinuous atomization Inhalation, six times a day

Eligibility

Sex/Gender

All

Age

15 Years to 85 Years

Inclusion criteria

Inclusion criteria: Abdominal Surgery Patients with Mechanical Ventilation duration more than 24h

Exclusion criteria

Exclusion criteria: 1. Patients with neuromuscular diseases; 2. Patients with heart-lung functions disorders

Design outcomes

Primary

Measure	Time frame
the rate of reintubation;the rate of pulmonary infection;	—

Secondary

Measure	Time frame
sputum amout in 24h;comfort level;degree of blood oxygen saturation;outcome of arterial blood gas analysis;sputum viscosity;	—

Countries

China

Contacts

Public ContactLi Li

smallsweetlily@hotmail.com+86 13817382212

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026