Paroxysmal atrial fibrillation (PAF)
Conditions
Interventions
Group A:No RoC and ATP induction (-)
Group B1:RoC and ATP induction (+) + second ablation
Group B2:No RoC and ATP induction (+) + no more ablation
Group C1:RoC + second ablation
Group C2:RoC + no more ablation
Sponsors
SIR RUN RUN SHAW Hospital of Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years; 2. Symptomatic paroxysmal AF, and underwent CPVI procedures which enhanced by ATP-induction and 30min observation; 3. Bidirectional block had been achieved in the initial CPVI procedures; 4. No AF recurrence in the follow-up (at least 1 year after initial CPVI procedure), and confirmed by 7-day-DCG; 5. To be able to and willing to provide the signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Stroke within the previous 3 months or documented intra-atrial thrombus; 2. Myocardial infarction within the previous 3 months or severe end-stage disease with A life expectancy of 2 years or less; 3. A contraindication to ATP or isoprenaline; 4. Abnormal liver or renal function; asthma; uncontrolled diabetes mellitus; hyperthyroidism; severe valvular heart disease; Chronic pericarditis; hypertrophic cardiomyopathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of freedom from atrial fibrillation post-CPVI;The effect of ATP-induction 1 year after the procedure;The recovery of pulmonary vein conduction after initial CPVI procedures; | — |
Countries
China
Contacts
Public ContactChenyang Jiang
Outcome results
None listed