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The effect of the preoperative oralcarbohydrate treatment attenuatingpostoperative insulin resistance in patients afterliver cancer resection

The effect of the preoperative oralcarbohydrate treatment attenuatingpostoperative insulin resistance in patients afterliver cancer resection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-10000821
Enrollment
Unknown
Registered
2009-12-25
Start date
2009-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

LIVER CANCER

Interventions

Experimental group:Preoperative oral 400ml solution containing 50g carbohydrate
Control group 30:Preoperative fasting 12h, 4h drink ban

Sponsors

WEST CHINA HOSPITAL, SICHUAN UNIVERSITY
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged from 18 to 65 years; 2. Patients with histologically confirmed hepatocellular carcinoma that receiving radical surgery; 3. newly diagnosed patients without anti-tumor therapy; 4. Child Pugh A or B; 5. Normal hepatic reserve function; 6. normal Fasting blood glucose level and OGTT tests outcomes. Exclude gastric emptying Disease, metabolic-related diseases, etc.; 7. Normal body mass index (19-25kg/m2); 8. WBC>4.0*10^9/L, Plt>100.0*10^9/L, Hb>90g/L.

Exclusion criteria

Exclusion criteria: 1. Metastasis; 2. Pregnant Woman and women during lactation; 3. Participating in other research projects; 4. Suffering from mental disease or patients with certain diseases affect the ability to understand the research requirements of the patient; 5. Upon inquiry, expressed his unwillingness to cooperate; 6. Received emergency surgery or laparoscopic surgery.

Design outcomes

Primary

MeasureTime frame
FFA;PKB, PI3K, GluT4 of mRNA expression;The level of insulin resistance;PTK activity;PKB, PI3K protein expression level;

Countries

China

Contacts

Public ContactSHU GONG
gdy-29@163.com+86 18980601474

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026