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Effects of Three at-home Bleaching Agents on Human Enamel: An In Situ vs. In Vitro Study

Effects of Three at-home Bleaching Agents on Human Enamel: An In Situ vs. In Vitro Study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-10000796
Enrollment
Unknown
Registered
2010-03-06
Start date
2010-03-16
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Human Enamel

Interventions

1:Bleaching agent A,gel,15mg,The bleaching gel will be put onto the surface of the samples 8 hours in a humid atmosphere at 37? every day, then wash away the gel. After that, the samples will be store
Group 2:Bleaching agent B, gel, 15mg, The bleaching gel will be put onto the surface of the samples 8 hours in a humid atmosphere at 37 degree C every day, then wash away the gel. After that, the samp
Group 3:Bleaching agent C, gel, 15mg, The bleaching gel will be put onto the surface of the samples 8 hours in a humid atmosphere at 37 degree C every day, then wash away the gel. After that, the samp
Group 4:Bleaching agent C, gel, 15mg, The bleaching gel will be put onto the surface of the samples 8 hours in a humid atmosphere at 37 degree C every day, then wash away the gel. After that, the samp
Group 5:Bleaching agent A, gel, 15mg, The bleaching gel will be put onto the surface of the samples 8 hours in a humid atmosphere at 37 degree C every day, then wash away the gel. After that, the samp
Group 6:Bleaching agent B, gel, 15mg, The bleaching gel will be put onto the surface of the samples 8 hours in a humid atmosphere at 37 degree C every day, then wash away the gel. After that, the samp
Group 7:Bleaching agent C, gel, 15mg. The bleaching gel will be put onto the surface of the samples 8 hours in a humid atmosphere at 37 degree C every day, then wash away the gel. After that, the samp
Group 8:No gel will be put onto the surface of the samples, all samples will be stored in artifi

Sponsors

School and Hospital of Stomatology, Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18 to 30 years old; 2. Normal saliva flow; 3. Absence of dental caries and/or periodontal disease; 4. Willing to perform bleaching treatment following the research schedule

Exclusion criteria

Exclusion criteria: 1. Use of orthodontic appliances; 2. Presence of fixed or removable denture; 3. Smokers; 4. Dentine sensitivity.

Design outcomes

Primary

MeasureTime frame
Surface morphology;Fracture toughness;Microhardness;

Countries

China

Contacts

Public ContactTao Jiang
jiangtao2006@whu.edu.cn+86 27 13098807738

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026