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Strategies To Prevent Renal Trauma -"START" trial: An Investigation on the Effect of Different Treatment Protocols in Minimizing Renal Injury during Extracoroperal Shock Wave Lithotripsy.

Strategies To Prevent Renal Trauma - "START" trial: An Investigation on the Effect of Different Treatment Protocols in Minimizing Renal Injury during Extracoroperal Shock Wave Lithotripsy.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-10000793
Enrollment
Unknown
Registered
2010-02-11
Start date
2010-02-17
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal stone

Interventions

Two groups:Extracorporeal Shock Wave Lithotripsy
Duration of intervention:45 minutes (2Hz) vs 1 Patients will receive increasing power of SWs from 25% to 80% within 20 shocks. This is the standard SWL treatment protocol in our centre. 2 Patients wil
(to be continued):4 Patients will receive 500 shocks at 40% power, followed by a 3-minute pause and then further SWs at 80% power until the end of whole treatment. 5 Patients will receive 500 shocks a

Sponsors

The Chinese University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Adult patient (aged >=18 years old); 2. Solitary radio-opaque renal stones of total size 5-20mm in maximal diameter as measured from plain radiography; 3. Clinically decided for SWL.

Exclusion criteria

Exclusion criteria: 1. Stones associated with any renal or ureteric anatomical abnormality, such as caliceal diverticulum, horseshoe kidney, ureteropelvic junction obstruction etc. 2. Patients with ureteric stent or nephrostomy tube inserted.

Design outcomes

Primary

MeasureTime frame
The difference of the degree of renal injury related to SWL as measured by a panel of urine markers.;

Secondary

MeasureTime frame
Patient tolerance to various protocols by assessment of analgesic demand and pain score during treatment;

Countries

China

Contacts

Public ContactLo Kin Yin Anthony
anthonylo@surgery.cuhk.edu.hk+852 26323186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026