Anisometropic amblyopia
Conditions
Interventions
Two groups:Refractive correction plus acupuncture plus near activities: full time spectacle correction is prescribed to each of the subject. The subjects are guided to have at least 1 hour of near act
Two groups:Five acupoints are selected, including “Baihui” (GV20), “Taiyang” (EX-HN5), “Cuanzhu” (BL2), “Hegu” (LI4) and “Fuyang” (BL59). Disposable acupuncture needles are inserted 1-20 mm in depth d
Two groups:Refractive correction plus patching plus near activities: full time spectacle correction is prescribed to each of the subject. Two hours of daily patching of the better-seeing eye is prescr
Sponsors
Nil
Eligibility
Sex/Gender
Male
Age
7 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Aged 7 to less than 13 years 2. Interocular visual acuity difference of >=2 logMAR lines; 3. Anisometropia of >= 0.50 diopters (D) of spherical equivalent and/or a >= -1.50-D difference between the eyes in astigmatism; 4. Visual acuity in the amblyopic eye of 0.3 - 0.8 logMAR for moderate amblyopia and of 0.8-1.3 logMAR for severe amblyopia; 5. Visual acuity in the sound eye >= 0.1 logMAR; 6. Myopic SE <= -6.00 D in the amblyopic eye; 7. No measurable heterotropia in primary gaze at distance or near fixation with their spectacles or a documented history of strabismus; 8. No other ocular cause for reduced acuity and no other prior treatment for amblyopia except for spectacle use. Spectacles, if needed, worn for at least 16 weeks or visual acuity documented to be stable; 9. Informed parental consent.
Exclusion criteria
Exclusion criteria: 1. Patients with ocular diseases other than refractive error and amblyopia; 2. Systemic diseases that require chronic or regular intermittent medication (e.g. Down Syndrome, asthma, allergy, epilepsy and so on); 3. Allergy to cycloplegics; 4. Inability to attend for follow up assessment; 5. Inability to tolerate and cooperate in acupuncture procedure; 6. Myopia more than -6.0D SE in the amblyopic eye.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity (BCVA) at each follow-up visit for both the amblyopic and sound eyes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Refractive errors, stereoacuity, the time to attain the stable acuity and RNFLT and macular thickness measurements by OCT.; | — |
Countries
China
Contacts
Public ContactProf. Dennis Shun Chiu Lam
Outcome results
None listed