A Comparison of Colloid and Saline for Intravascular Volume Replacement Therapy in the Patients of Hepatic Cellular Carcinoma Undergoing Partial Hepatectomy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-10000790

Enrollment

Unknown

Registered

2010-01-14

Start date

2010-04-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatic cellular carcinoma

Interventions

Group A:HES (Voluven) 1000ml intervenously supplied daily for postoperative 3 days and reduced to 500ml/d for the following 2 days

Group B:lactated Ringer's (RL) solution alone intervenously supplied for postoperative 5 days according to Hemodynamic

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Male and female aged 18 to 65 years old; 2. Able and willing to provide signed informed consent; 3. patients of hepatic cellular carcinoma with liver cirrhosis undergoing partial hepatectomy.

Exclusion criteria

Exclusion criteria: 1 .Patients with renal insufficiency requiring dialysis; 2. severe liver insufficiency (Child C); 3. severe hypoproteinemia( 10*10^9/L, body temperature >38.0 degree C); 7. allergy to starch preparations.

Design outcomes

Primary

Measure	Time frame
biochemical indices of liver function;plasma osmolality;inflammatory response factors;	—

Secondary

Measure	Time frame
biochemical indices of renal function;Hemodynamic;	—

Contacts

Public ContactLu-Nan Yan

yangjian888_0_0@126.com+86 13408418675

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026