Chronic Obstructive Pulmonary Disease(COPD)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with Stable COPD; 2. Aged from 18-80 years; 3. Signed and dated written informed consent obtained from the subject and/or subject's legally acceptable representative prior to study participation.
Exclusion criteria
Exclusion criteria: 1. Weekness patients, dehydration, diarrhea(>3 time everyday) and with swirl symptom; 2. Patients no response with thrill laxative(such as rheum offcinale, Senna leaf, casror oil); 3. Patients with mechanicalintestinal obstruction, peritonitis, hernia, intestinal stenosis, haemorrhoids, arterial aneurysm, anemia, enteromegalia,cirrhosis, intestinal cancer, anal fistula, acute left heartfailure, acute cerebral hemorrhage,alimentary tract hemorrhage, aplastic anemia, and acute renal failure; 4. Comorbidity of mental illness, severe neurologic impairment (such as aphasia, agnosia), or for other reasons unable to cooperate with investigators; 5. Patients with airflow limitation due to bronchiectasis, cystic fibrosis, active tuberculosis, lung cancer, and other respiratory diseases; 6. Primary heart, liver, kidney, or hematopoietic system illnesses; 7. Recent use of immunosuppressive agents; 8. Women who are pregnant or breast-feeding; 9. Patients with drug allergy or known allergy to components of drugs used in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| frequency of acute exacerbation;SGRQ;6MWD;symptom; | — |
Secondary
| Measure | Time frame |
|---|---|
| lung function; | — |
Countries
China