The extracerebral tumor origing from the skull base
Conditions
Interventions
A:Normal surgical procedure to rebuild the skull bas
B:Normal procedure following by the arachnoial separation and the reconstruction of the dural sac with artificial dura material
C:Normal procedure following by the arachnoial separation and the reconstruction of the dural sac with the periosteum and artificial dura combined material
Sponsors
The affilliated Nanfang Hospital of the Sourthern Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The extracerebral tumor origing from the skull base (meningiomas, chordoma, pituitary adenomas, acoustic neuroma, trigeminal nerve schwannoma, sellar craniopharyngiomas, bone neoplasms, et al); 2. The primary treated by transcranial surgery; 3. Without undergoing postoperative radiotherapy; 4. Tumor recurrence occuring during the research period; 5. The secondary transcranial operation used to treat the reccurence tumor; 6. Sufficient clinical recording, experimental detection, pre- and postoperative MR and CT images; 7. The subjects or their guardian signed a study consent form before enrollment.
Exclusion criteria
Exclusion criteria: 1. Intracerebral tumor; 2. The primary palliative treatment or treated by transsphenoidal approach; 3. Undergoing the postsurgical common or focus radiotherapy; 4. Loss follow-up or without the sufficient clinical database.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2. To evaluate the tumoral growth pattern and the anatomical relationship of the normal brain tissue;5.Glasgow outcome;1. The complication incidence after the primary surgery (CSF leak, Intracranial infection, Meningitis, brain abscess, intracranial product gas);4. The complication after the secondary surgery (Disfunction of the nervous system, Brain contusion,;3.During the reoperation, the tumoral morphology; | — |
Countries
China
Contacts
Public ContactSongtao Qi
Outcome results
None listed